Acute toxicity, biochemical and histological of fenitrothion and thiobencarb on fish Nile tilapia (Oreochromis niloticus)

Abstract. Fouad MR, El-Aswad AF, Aly MI. 2022. Acute toxicity, biochemical and histological of fenitrothion thiobencarb on fish Nile tilapia (Oreochromis niloticus). Nusantara Bioscience 14: 217-226. The results show that the tested are highly toxic to fish. However, is more (1.6 times) Oreochromis niloticus (Linnaeus, 1758) than thiobencarb. determined 96-h LC50 values using a static bioassay system fingerlings (8-10 g) were 0.20 0.32 mg L-1 for thiobencarb, respectively. mortality rate exposed ½ (0.10 mg/L) (0.16 four days demonstrated was 20% rate. Fish showed tremors, lethargy, decreased movement, increased respiratory rhythm. total activity AChE in control 5.61 ±0.03; it significantly reduced 4.92 ±0.03 treatment 1.13 ±0.02 treatment. Fenitrothion specific from 0.83 ±0.01 0.68 ±0.01, whereas 0.22 ±0.01. Generally, inhibited much fenitrothion; produced 80% inhibition, while 12.5% inhibition. It significant increase liver GST SOD pesticides compared control. There no alterations tissues individuals. found herbicide affected gills, kidneys, insecticide fenitrothion.